The present study was undertaken to investigate the developing mechanism and its
biological significance of the decidua.
Unilateral salpingeal ligation was performed on mature female Sprague-Dawley rats.
Mating was proceeded. On the 3rd, 5 th, 7th, and 9th days of the pregnancy,
morphological changes of both ligated (non, pregnant horn) and non, ligated (pregnant
horn) salpinges were observed.
Gradual change of the decidualization was observed already by the 5 th day of the
pregnancy in the non-ligated horn, but was not in ligated.
Marked change of the decidualigation was observed by the 7th and 9th days of
pregnancy in the non-ligated horn, but little change T, as in the ligated.
The results suggest that decidualigation is contributed not only by endocrinologicl
factors but also obviously by some factors of the blastocyst.
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